关键词: 抽动障碍, 抽动障碍共患注意力缺陷多动障碍, 儿童

Abstract: Objective To analyze the clinical characteristics of tic disorders (TD) in children with and without attention deficit hyperactivity disorder (ADHD),in order to provide ideas for clinical treatment.Methods A total of 408 children aged 6 to 12 years old with TD-only and TD+ADHD were randomly selected from Pediatric Department,Guang'anmen Hospital,China Academy of Chinese Medical Sciences from June 2018 to November 2019,including 296 children with TD-only and 112 children with TD+ADHD.The differences on the incidence,such as disease course,clinical subtypes,onset age of TD,severity of TD between the two groups were compared,and the distribution of ADHD in TD+ADHD group were analyzed.Results In terms of Yale Global Tic Severity Scale(YGTSS) score and damage ratio,the TD+ADHD group was significantly higher than the TD alone group(t=-23.24,-19.17,P<0.001),which were not affected by the ADHD subtype.In TD+ADHD group,the score of attention-deficit subscale was significantly higher than that of hyperactivity/impulsivity (t=2.96,P＜0.05).The age of TD comorbid with hyperactivity/impulsiveness of ADHD (TD+ADHD-HI) and TD comorbid with the mixed of ADHD (TD+ADHD-C) was lower than that of TD comorbid attention-deficit of ADHD (TD+ ADHD-I) (F=7.93,P=0.019).Conclusions The condition is more serious in children with TD+ADHD,but the severity is not affected by the ADHD subtype.Moreover,compared with TD+ADHD-I,the early behavioral problems of TD+ADHD-HI and TD+ADHD-C are more prominent and easy to be early identified.However,the attention deficit of children with TD+ADHD-I is usually very serious when seeing doctors.

Key words: tic disorders, tic disorder with attention deficit hyperactivity disorder, children