胞外体与病毒感染的研究进展

中国儿童保健杂志 ›› 2011, Vol. 19 ›› Issue (2): 143-145.

胞外体与病毒感染的研究进展

阎贝贝¹ 综述,卢宪梅¹,邓景畅² 审校

1 山东大学齐鲁医院儿科,山东济南 250012;
2 山东大学医学院生化教研室,山东济南 250012

收稿日期:2010-10-08 发布日期:2011-02-06 出版日期:2011-02-06
作者简介:阎贝贝(1984-),女,山东人,在读研究生,主要研究方向为新生儿疾病
基金资助:
山东省自然科学基金(ZR2009CM075)

Received:2010-10-08 Online:2011-02-06 Published:2011-02-06

摘要/Abstract

摘要： 胞外体(exosome,EXO)起源于多种真核细胞多泡体(multivesicular body,MVBs)的内部小囊泡,MVBs与细胞膜融合后即释放出EXO,其功能决定于来源的细胞。作为细胞间信息传递的新方式,EXO逐渐成为各领域的研究热点。本文就EXO的功能及作用做一综述,着重在病毒感染方面。在病毒感染的过程中,EXO不仅可以作为病毒感染和传播的重要方式,在介导病毒的免疫逃逸和免疫耐受中也扮演了重要角色。

关键词: 胞外体, 外质体, 外来体, 病毒, 感染

中图分类号:

R722.1

阎贝贝审校. 胞外体与病毒感染的研究进展[J]. 中国儿童保健杂志, 2011, 19(2): 143-145.

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