325例辅助受孕儿24月龄时精神运动发育水平研究

中国儿童保健杂志 ›› 2012, Vol. 20 ›› Issue (10): 878-880.

325例辅助受孕儿24月龄时精神运动发育水平研究

赵倩¹,潘琼²,邹小英¹,周细中¹, 张清学³,李宏¹

南方医科大学珠江医院1 儿科,2 妇产科,广东广州 510282;
3 中山大学第二附属医院辅助生殖中心,广东广州 510120

收稿日期:2012-04-20 发布日期:2012-10-06 出版日期:2012-10-06
通讯作者: 李宏,E-mail:lh32998@126.com
作者简介:赵倩(1974-),女,硕士学位,主要研究方向为婴幼儿精神运动发育评估及早期干预
基金资助:
广东省科技计划项目(2007B030501006)

Psychomotor development at 24 months old in 325 children conceived with use of assisted reproductive technology

ZHAO Qian¹,PAN Qiong²,ZOU Xiao-ying¹,ZHOU Xi-zhong¹,ZHANG Qing-xue³,LI Hong¹

1 Department of Pediatrics;
2 Department of Obstetrics and Gynecology,Zhujiang Hospital of Southern Medical University,Guangzhou,Guangdong 510282,China;
3 Department of Reproductive Center,the Second Affiliated Hospital of SUN Yat-sen University,Guangzhou,Guangdong 510120,China

Received:2012-04-20 Online:2012-10-06 Published:2012-10-06

摘要/Abstract

摘要： 【目的】通过研究辅助受孕儿24月龄时的精神运动发育水平,以评价辅助生殖技术的安全性。【方法】采用前瞻性对照研究方法,实验组为人工辅助受孕妊娠儿,对照组为自然受孕妊娠儿,将两组人群在母亲年龄、产次、家庭社会阶层、双亲受教育程度等几个方面进行配对,均自母亲孕28周起入组登记定期随访收集相关资料并由经过培训的指定专业人员采用CDCC婴幼儿发育量表定期对其行精神运动发育评估至24月龄,获得智力发育指数及运动发育指数。【结果】辅助受孕儿童至24月龄时其精神运动发育水平与自然受孕儿童相比差异无统计学意义(P>0.05)。【结论】辅助受孕儿童24月龄时的精神运动发育水平正常,初步证明我国目前的辅助生殖技术是安全的。

关键词: 辅助生殖技术, 精神运动发育, 对照研究

Abstract: 【Objective】 To compare the psychomotor development at 24 months old in children born after assisted conception with a control group of children conceived naturally. 【Methods】 A mached control study was performed on the psychomotor development of 24 months old in children conceived with use of assisted reproductive technology.The control group was matched according to maternal age,parity,social class and level of maternal education.The suitable mothers were invited to participate at 28 weeks of gestation and were followed up to delivery.The children of two groups were followed up to 24 months old and a formal developmental assessment was done with the CDCC Scales of Children Development. 【Result】 No statistically significant differences were found in the mental development index (MDI) and psychomotor development index (PDI) between study and control groups,as asssessed by the CDCC Scales. 【Conclusion】 The level of psychomotor development at 24 months old in children born after assisted conception was normal.So the assisted reproductive technology is safety in china.

Key words: assisted reproductive technology, psychomotor development, control study

中图分类号:

R749.94

赵倩,潘琼,邹小英,周细中, 张清学,李宏. 325例辅助受孕儿24月龄时精神运动发育水平研究[J]. 中国儿童保健杂志, 2012, 20(10): 878-880.

ZHAO Qian,PAN Qiong,ZOU Xiao-ying,ZHOU Xi-zhong,ZHANG Qing-xue,LI Hong. Psychomotor development at 24 months old in 325 children conceived with use of assisted reproductive technology[J]. journal1, 2012, 20(10): 878-880.

参考文献

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