关键词: 腹泻, 轮状病毒, 流行病学, 儿童

Abstract: 【Objective】 To investigate the epidemiological characteristics of the children infected with rotavirus in Hangzhou,and to provide evidence to prevent and cure the children with acute diarrhea caused by rotavirus infection. 【Method】 The antigen assay of rotavirus in stool from the outpatient and inpatient children with acute diarrhea was employed in 2007-2011,and the positive patient information was statistically analyzed. 【Results】 The rotavirus-positive rate of the children of Hangzhou was 29.25% in 2007-2011,the annual rotavirus-positive rate decreased from 39.42% in 2007 to 19.61% in 2011.The epidemic period of children rotavirus was mainly in November and December of every year,and the children aged 6~18 months had the high infection rate.The rotavirus-positive rate was 32.28% in outpatient children with diarrhea,and the positive rate was 20.70% in hospitalized children. 【Conclusion】 The children rotavirus infection rate was lower than the national average level in Hangzhou,the safe and effective rotavirus vaccine development may eradicate the hazards of children rotavirus in the prevention and treatment of children rotavirus.

Key words: diarrhea, rotavirus, epidemiology, children