早产儿颅内出血相关因素的临床分析

doi:10.11852/zgetbjzz2015-23-10-28

中国儿童保健杂志 ›› 2015, Vol. 23 ›› Issue (10): 1099-1100.DOI: 10.11852/zgetbjzz2015-23-10-28

早产儿颅内出血相关因素的临床分析

董燕¹,杜开先¹,贾天明¹,张晓莉¹,徐发林²

郑州大学第三附属医院1 神经内科;
2 新生儿科,河南郑州 450000

收稿日期:2015-04-20 发布日期:2015-10-10 出版日期:2015-10-10
作者简介:董燕(1981-),女,主要研究方向为小儿神经。

Clinical study on the related factors of the intracranial hemorrhage in premature infants.

DONG Yan¹,DU Kai-xian¹,JIA Tian-ming¹,ZHANG Xiao-li¹,XU Fa-lin².

1.Department of Neurology;
2.Division of Neonatology,the Third Affiliated Hospital of Zhengzhou University,Zhengzhou,Henan 450000,China

Received:2015-04-20 Online:2015-10-10 Published:2015-10-10

摘要/Abstract

摘要： 目的探讨早产儿颅内出血(intracranial hemorrhage,ICH)相关因素,为预防脑室周围-脑室内出血(periventricular-intraventricular hemorrhage,PIVH)、脑实质出血、蛛网膜下腔出血提供参考依据。方法选择2013年4月-2014年3月住院的确诊ICH的早产儿为病例组,同期住院非ICH早产儿为对照组,对相关因素进行回顾性研究。单因素分析用χ²检验,多因素分析用多元Logistic 回归分析。结果 Logistic回归分析确定宫内窘迫、胎龄小于34周、机械通气、电解质紊乱为早产儿ICH独立危险因素,产前应用地塞米松是ICH的有利因素。结论加强对高危孕产妇孕期监测,及时发现和处理妊娠合并症,产前适时应用地塞米松等可减少早产儿ICH的发生。

关键词: 早产儿, 颅内出血, 相关因素, 临床分析

Abstract: Objective To investigate a variety of related factors for intracranial hemorrhage(ICH) in premature infants. Methods A case-control study was performed between cases with ICH and cases of non-ICH premature infants.All the subjects were the in-patient newborns from April 2013 to March 2014.Data of the related factors were processed with both χ² test and multiple Logistic regression analysis. Results The statistic analysis showed that fetal distress,gestational age ＜34 weeks,mechanical ventilation and electrolyte disturbance were significant risk factors for ICH.Prenatal application of dexamethasone was a favorable factor. Conclusions In order to prevent and cure ICH at an early stage,monitoring of high risk gravida,correct management of complications,prenatal application of dexamethasone and so on should be advocated.

Key words: premature infants, intracranial hemorrhage, related factors, clinical study

中图分类号:

R179

董燕,杜开先,贾天明,张晓莉,徐发林. 早产儿颅内出血相关因素的临床分析[J]. 中国儿童保健杂志, 2015, 23(10): 1099-1100.

DONG Yan,DU Kai-xian,JIA Tian-ming,ZHANG Xiao-li,XU Fa-lin.. Clinical study on the related factors of the intracranial hemorrhage in premature infants.[J]. journal1, 2015, 23(10): 1099-1100.

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早产儿颅内出血相关因素的临床分析

Clinical study on the related factors of the intracranial hemorrhage in premature infants.

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