关键词: 癫痫, 脑性瘫痪, 儿童, 危险因素

Abstract: Objective To analysis the risk factors of cerebral palsy (CP) children with secondary epilepsy risk factors and provide reference for the prevention and treatment of CP children with epilepsy seizures. Methods Clinical data of 477 cases of children with CP in our hospital from May 2008 to January 2015 were retrospective analyzed.According to the children in hospital had seizures or not,children were divided into epilepsy group (case group) and the non-epilepsy group (control group),the general clinical data and imaging data of two groups were comparied,and the related factors were analyzed by Logistic regression analysis. Results In 477 patients with CP,86 cases merge epilepsy (18.0%),most (61.6%) children with epilepsy with tetraplegia,stiffness matrix cramps seizure was the main type of seizures (44.2%).Multiariable Logistic regression analysis suggested that low birth weight (OR=2.793,P<0.05),the softening of the brain (OR=3.185,P<0.05),intracranial hemorrhage (OR=3.581,P<0.05),the structure of the brain malformation (OR=5.839,P<0.05) were independent risk factors of CP children with epilepsy. Conclusions In children with CP,a softening of the brain,intracranial hemorrhage,low birth weight and brain structure abnormalities significantly increased the risk of epilepsy,which should be given clinical attention.   

Key words: epilepsy, Cerebral palsy, Children, Risk factors for