关键词: 肥胖, 代谢综合征, 膳食纤维, 运动, 干预, 儿童

Abstract: Objective To explore the clinical features of glucose and lipid metabolism in obese children and analyse the effects of dietary fiber and exercise intervention. Methods 110 obese children visiting our hospital from June 2013 to November 2014 were enrolled as obesity and 90 lean children were selected as normal control.Height,weight,waist circumference and hip circumference of all chilgren were measured,and the BMI was calculated.Differences in anthropometric data were compared between the two groups.At the same time,the obese children were randomly classified into two groups:clinical trial group (55 children) and control group (55 children).The clinical trial group were given dietary fiber food and exercise intervention for five weeks,while the control group were just given general direction.The biochemical paramaters including glucose metabolism,lipid metabolism,protein metabolism and the blood pressure in all the children were measured. Results The waist circumference,hip circumference,weight and BMI in the obese group were significantly higher compared to the normal lean group (P＜0.05).After intervention,the weight,BMI,waist circumference,plasma glucose,postprandial glucose,total cholesterol,triglyceride,high density lipoprotein and blood pressure in the clinical trial group were declined compared to the control group.Whereas there was no differences in low density lipoprotein cholesterol between between the two groups(P＞0.05). Conclusions Obese children have disturbances in clinical characteristics.Dietary fiber toghther with exercise intervention may be benefit for improving the disorders in glucose and lipid metabolism and blood pressure.

Key words: obesity, metabolic syndrome, dietary fiber, exercise, intervention, children