关键词: 孤独症谱系障碍, 早期诊断, 早期筛查

Abstract: Objective To investigate factors affecting the early diagnosis of autism spectrum disorders (ASD) in order to provide evidence for further research and policy. Methods Totally 207 ASD cases under six years old diagnosed at Shenzhen Maternity and Child Health care Hospital were recruited,and their caregivers were asked to finish a field survey or telephone survey.According to the diagnostic months,participants were divided into early diagnosis group(n=48,23.19%) and later diagnosis group(n=159,76.81%).Univariate analysis and stepwise Logistic regression analysis were used to compare the influencing factors on questionnaire,results of Gesell Development Diagnosis Scales (GDDS) and Baby-junior high school students ability of social life scale(S-M) between the two groups. Results The two groups were different in 11 factors,such as an early screening of ASD,the main caregivers.Multivarite Logistic analysis showed that early screening of ASD was an favorable factor(OR=4.296,95%CI:1.959~9.423).The more seriously disabled degree of ability for social life(OR=0.380,95%CI:0.207~0.698)and gross motor skill(OR=0.323,95%CI:0.185~0.564),the worse it was for early diagnosis. Conclusion Since the early screening plays a crucial role at early diagnosis,the process of early screening for ASD should be improved.

Key words: autism spectrum disorders, early diagnosis, early screening