关键词: 社区获得性肺炎, 住院患儿, 病原学分析, 预后, 影响因素

Abstract: Objective To analyze the pathogens of community acquired pneumonia (CAP) of hospitalized children and the factors influencing prognosis. Methods A total of 280 CAP children hospitalized in Baoding Children′s Hospital from February 2014 to September 2016 were enrolled as the research subjects, and were divided into good prognosis group and poor prognosis group according to the treatment results. The blood and respiratory secretions were cultured to identify pathogenic microorganisms. And Logistics regression analysis was used to determine the influencing factors of CAP prognosis. Results Mycoplasma pneumoniae was the main pathogen of CAP in hospitalized children. Respiratory syncytial virus infection (over 50%) was main type of CAP virus. Streptococcus pneumoniae infection was the main type of CAP bacteria. Children under 3 years old(OR=0.298,95%CI:0.128~0.692), the occurrence heart failure(OR=0.690,95%CI:0.555~0.858)were the unfavorable factors of good prognosis in hospitalized CAP children. Invasive mechanical ventilation treatment(OR=2.257,95%CI:1.709~2.981) and antibacterial drug combination(OR=1.587,95%CI:1.135~2.219)were favorable factors for initial prognosis of children with good hospital CAP. Conclusion The order from high to low of pathogens in hospitalized children with CAP is mycoplasma, viruses and bacteria. Factors beneficial to prognosis include invasive mechanical ventilation and initial antimicrobial drug combination.

Key words: community acquired pneumonia, hospitalized children, etiology analysis, prognosis, influencing factors