关键词: 延迟脐带结扎, 中晚期早产儿, 贫血, 结局, 并发症

Abstract: Objective To investigate the influence of delayed cord clamping (DCC) on the outcome of moderate and late preterm infants(MPIs), in order to provide reference for improring the outcome of MPIs. Methods Totally 116 cases of moderate and late preterm infants delivered in the Affiliated Hospital of Weifang Medical University from January 2016 to January 2017 were randomly divided into delayed cord clamping(DCC)group (n=55) and early cord clamping (ECC) group (n=61).The Apgar score of 1 min and 5 min, the level of hemoglobin (Hb) and hematocrit(HCT) in 12 hours,1 week and 4 weeks after birth, bilirubin peak, the time for bilirubin arriving peak, and the incidence rates of anemia, blood transfusion, erythrocytosis, intracranial hemorrhage, sepsis and respiratory distress syndrome (RDS) were compared between DCC group and ECC group. Results The levels of hemoglobin and hematocrit in 12 hours,1 week and 4 weeks after birth in DCC group were significantly higher than those in ECC group (all P<0.05).The incidence rates of anemia in 4 weeks after birth and blood transfusion during hospitalization in DCC group were also significantly lower than those in ECC group (all P<0.05).However, there were no significant differences on the Apgar score of 1 min and 5 min, bilirubin peak, the time for bilirubin arriving peak, and the incidence rates of erythrocytosis, intracranial hemorrhage, sepsis, RDS between DCC group and ECC group (P>0.05). Conclusions Delayed cord clamping can increase hemoglobin and hematocrit levels in moderate and late preterm infants, reduce the incidence of anemia and blood transfusion. Meantime, delayed cord clamping do not increase the incidence of complications, so it can be used to improve the outcome of moderately and late preterm infants.

Key words: delayed cord clamping, moderate and late preterm infants, anemia, outcome, complication