关键词: 湿疹, 发病率, 过敏疾病家族史, 影响因素, 婴儿
中图分类号:R179 文献标识码:A 文章编号:1008-6579(2015)10-1070-04 doi:10.11852/zgetbjzz2015-23-10-19

Abstract: Objective To compare the incidence and predisposing environmental factors of eczema in different allergic family history infant. Methods Totally 270 healthy,term newborns enrolled into this study and was followed up to one year old.Informations including allergic family history,delivery mode,environmental smoking exposure and diet during maternal and infancy etc,were recorded during the follow-up period.Multifactors logistic regression was used to analyze the environmental risk factors of eczema in different allergic family history infant. Results The incedence of infantile eczema was 64.8% (175/270).There was no significant difference between the prevalence of eczema in infants with or without allergic family history(63.9% vs 65.5%,P>0.05).However,logistic regression analysis showed,although no environmental risk factors were found for eczema in infants with allergic family history,for infants without allergic family history,born in autumn and winter were suffering 4.912 times of infantile eczema risk than that of born in spring and summer,OR4.921(95%CI:1.102～8.103,P=0.032),and exclusive breastfeeding within the first 4 months might decrease the risk of infantile eczema,OR0.013(95%CI:0.009～0.518,P=0.020). Conclusions The prevalence of infantile eczema in this study is higher than other literatures.Allergic family history seems have no effect on the prevalence of infantile eczema.However,for infants without allergic family history,exclusive breastfeeding during the first 4 months might be benefit to reduce the incidence of infantile eczema.Moreover,born in autumn and winter seems to be the risk factors of eczema for infants without allergic family history.

Key words: eczema, incidence, allergic family history, influencing factors, infant