关键词: 高胆红素血症, 胆红素脑病, 脑干听觉诱发电位, 磁共振成像

Abstract: Objective To explore the early diagnostic value of brainstem auditory evoked potential(BAEP) and magnetic resonance imaging(MRI) in the neonates with bilirubin encephalopathy. Methods Retrospective analysis of the relared clinical indicators in 137 neonates with hyperbilirubinemia. Results The levels of serum total bilirubin,serum total bilirubin/albumin were higher in the neonates with abnormal BAEP,abnormal MRI and acute bilirubin encephalopathy than those with normal BAEP,normal MRI and without cute bilirubin encephalopathy (P<0.05).Abnormal rate of BAEP was positively correlated to that of MRI (r=0.466,P<0.05).On the diagnosis of bilirubin encephalopathy,the sensitivity of BAEP(87.18%) was higher than MRI (64.10%),but the specificity of BAEP(78.57%) was lower than MRI(93.88%). Conclusion BAEP and MRI examinations have important clinical value in the early diagnosis of bilirubin encephalopathy in the neonates.

Key words: hyperbilirubinemia, bilirubin encephalopathy, brainstem auditory evoked potential, magnetic resonance imaging