journal1 ›› 2020, Vol. 28 ›› Issue (11): 1231-1233.DOI: 10.11852/zgetbjzz2019-1531

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Research advances on the influence of intestinal flora on neonatal necrotizing enterocolitis

WANG Zhen, YANG Shu-fen   

  1. The Second Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang 150086,China
  • Received:2019-12-14 Revised:2020-02-27 Online:2020-11-10 Published:2020-11-10
  • Contact: YANG Shu-fen,


王朕, 仰曙芬   

  1. 哈尔滨医科大学附属第二医院,黑龙江 哈尔滨 150086
  • 通讯作者: 仰曙芬,
  • 作者简介:王朕(1992-),男,黑龙江人,硕士研究生,主要研究方向为儿童保健。

Abstract: Previously,neonatal necrotizing enterocolitis is considered to be related to factors such as preterm birth,hypoxia,artificial feeding,sepsis,intestinal ischemia,and intestinal pathogenic bacteria infection.In recent years,a growing number of studies have shown that intestinal flora disorders also play an important role in the pathogenesis of neonatal necrotizing enterocolitis.This article reviews the effect of intestinal flora on neonatal necrotizing enterocolitis,hoping to provide a reference for the prevention and treatment of neonatal necrotizing enterocolitis.

Key words: intestinal flora, colitis, newborn

摘要: 以前,人们认为新生儿坏死性小肠结肠炎与早产、缺氧、人工喂养、败血症、肠缺血和肠道致病菌感染等因素有关。近些年来,不断增多的研究结果显示,肠道菌群失调在新生儿坏死性小肠结肠炎的发病中也扮演重要角色。本文就肠道菌群对新生儿坏死性小肠结肠炎的影响进行综述,以期为新生儿坏死性小肠结肠炎的防治提供参考。

关键词: 肠道菌群, 结肠炎, 新生儿

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