Application of noninvasive brain stimulation in children with psychological disorders treatment

doi:10.11852/zgetbjzz2020-1257

Abstract

Abstract: With regard to the psychological disorders of adolescents, noninvasive brain stimulation (NIBS) technique is one of the most advanced physical therapy, and its clinical effects have attracted much attention in the recent years. The NIBS techniques consist of transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS). Therefore, this article mainly focuses on the working principles of the two techniques and their therapeutic application in major depressive disorder in youth, attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD), respectively. Furthermore, the article emphasizes that NIBS technique has potential in the treatment of children's psychological disorders, and the artificial intelligence is critical to its development.

Key words: transcranial magnetic stimulation, transcranial direct current stimulation, major depressive disorder in youth, attention deficit hyperactivity disorder, autism spectrum disorder

摘要： 无创神经脑刺激治疗儿童心理障碍是当下较为先进的物理治疗手段。本文着重介绍了无创神经脑刺激的两种代表技术-经颅磁刺激与经颅直流电刺激的工作原理,两者分别在儿童抑郁症、注意缺陷多动障碍与孤独症谱系障碍中的治疗应用,以及对无创神经脑刺激在儿童心理障碍治疗中存在的问题与未来的发展,其中人工智能的引用是其发展很具潜力的方向。

关键词: 经颅磁刺激, 经颅直流电刺激, 儿童抑郁症, 注意缺陷多动障碍, 孤独症谱系障碍

CLC Number:

R749.94

BAI Hai-ping, YUAN Yuan. Application of noninvasive brain stimulation in children with psychological disorders treatment[J]. Chinese Journal of Child Health Care, 2021, 29(4): 397-400.

白海萍, 袁媛. 无创神经脑刺激在儿童心理障碍治疗中的应用[J]. 中国儿童保健杂志, 2021, 29(4): 397-400.

References

[1] Lazzaro VD, Rothwell JC, Capogna M, et al. Noninvasive stimulation of the human brain:activation of multiple cortical circuits[J]. Neuroscientist, 2018, 24(3):246-260.
[2] Hong YH, Wu SW, Pedapati EV, et al. Safety and tolerability of theta burst stimulation vs. single and paired pulse transcranial magnetic stimulation:a comparative study of 165 pediatric subjects[J]. Front Aging Neurosci, 2015:29-29.doi:10.3389/fnhum.2015.00029
[3] Klimesch W, Sauseng P, Gerloff C. Enhancing cognitive performance with repetitive transcranial magnetic stimulation at human individual alpha frequency[J].Eur J Neurosci,2015, 17(5):1129-1133.
[4] Bikson M, Grossman P, Thomas C, et al. Safety of transcranial direct current stimulation:evidence based update 2016[J]. Brain Stimul, 2016, 9(5):641-661.
[5] Xu DD, Rao W, Cao XL, et al. Prevalence of major depressive disorder in children and adolescents in China:A systematic review and meta-analysis[J]. J Affect Disorders, 2018, 1(1):592-598.
[6] Hare BD, Duman RS. Prefrontal cortex circuits in depression and anxiety:contribution of discrete neuronal populations and target regions[J]. Mol Psychiatry, 2020. https://www.nature.com/articles/s41380-020-0685-9.
[7] Macmaster FP, Croarkin PE, Wilkes TC, et al. Repetitive transcranial magnetic stimulation in youth with treatment resistant major depression[J]. Front Psychiatry, 2019, 10(170):1-6.
[8] 王鹭, 冯虹, 徐炯炯, 等. 经颅磁刺激联合认知疗法治疗儿童首发抑郁症观察[J]. 医学研究杂志, 2018, 47(9):124-126.
[9] Fregni F, Boggio PS, Nitsche MA, et al. Treatment of major depression with transcranial direct current stimulation[J]. Bipolar Disorders, 2006, 8(2):203-204.
[10] Bennabi D, Nicolier M, Monnin J, et al. Pilot study of feasibility of the effect of treatment with tDCS in patients suffering from treatment-resistant depression treated with escitalopram[J]. Clin Neurophysiology, 2015, 126(6):1185-1189.
[11] American psychiatric Association. Diagnostic and statistical manual of mental disorders:DSM-5 [M]. 5th ed. Washington DC:American Psychiatric Association, 2013.
[12] 成梅, 杨燕, 尹华站. 经颅直流电刺激在注意缺陷多动障碍治疗中的应用[J]. 心理科学进展, 2018, 26(4):657-666.
[13] Niederhofer H.Effectiveness of the repetitive transcranial magnetic stimulation (rTMS) of 1Hz for attention-deficit hyperactivity disorder (ADHD)[J]. Psychiat Danub, 2008, 20(1):91-92.
[14] Cao P, Xing J, Cao Y, et al. Clinical effects of repetitive transcranial magnetic stimulation combined with atomoxetine in the treatment of attention-deficit hyperactivity disorder.[J]. Neuropsych Dis Treat, 2018, 1(14):3231-3240.
[15] Lee J, Lewis CP, Daskalakis ZJ, et al. Transcranial direct current stimulation:considerations for research in adolescent depression[J]. Front Psychiatry, 2017, 8(91):1-9.
[16] Soff C, Sotnikova A, Christiansen H, et al. Transcranial direct current stimulation improves clinical symptoms in adolescents with attention deficit hyperactivity disorder[J]. J Neural Transm, 2017, 124(1):133-144.
[17] Allenby C, Falcone M, Bernardo L, et al. Transcranial direct current brain stimulation decreases impulsivity in ADHD[J]. Brain Stimul, 2018, 11(5):974-981.
[18] Soltaninejad Z, Nejati V, Ekhtiari H, et al. Effect of anodal and cathodal transcranial direct current stimulation on DLPFC on modulation of inhibitory control in ADHD[J]. J Atten Disord, 2019, 23(4):325-332.
[19] Sun X, Allison C, Wei L, et al. Autism prevalence in China is comparable to Western prevalence[J]. Mol Autism, 2019, 10(1):1-19.
[20] Tsuchiyagaito A, Hirano Y, Asano K, et al. Cognitive-behavioral therapy for obsessive-compulsive disorder with and without autism spectrum disorder:gray matter differences associated with poor outcome[J]. Front Psychiatry, 2017, 8:143.
[21] Enticott PG, Fitzgibbon BM, Kennedy HA, et al. A double-blind, randomized trial of deep repetitive transcranial magnetic stimulation (rTMS) for autism spectrum disorder[J]. Brain Stimul, 2014, 7(2):206-211.
[22] 党卫民, 金怡, 黄悦勤, 等.重复经颅磁刺激治疗儿童孤独症的初步研究[J]. 中国神经精神疾病杂志, 2009, 35(8):505-506.
[23] 柯晓殷, 张英, 操小兰, 等. 经颅磁刺激治疗后孤独症谱系障碍儿童表情识别过程神经活动的变化[J]. 中国心理卫生杂志, 2019, 33(6):406-410.
[24] 佟祯, 丁萌, 李小俚, 等. 低频重复经颅磁刺激对孤独症儿童脑电节律的影响[J]. 生物医学工程学杂志, 2018, 35(3):337-342.
[25] Amatachaya A, Jensen MP, Patjanasoontorn N, et al. The short-term effects of transcranial direct current stimulation on electroencephalography in children with autism:a randomized crossover controlled trial[J]. Behav Neurol, 2015, 1(1):928631.
[26] Gómez L, Vidal B, Maragoto C, et al. Non-invasive brain stimulation for children with autism spectrum disorders:a short-term outcome study[J]. Syst Res Behav Sci, 2017, 7(3):1-12.
[27] Costanzo F, Menghini D, Casula L, et al. Transcranial direct current stimulation treatment in an adolescent with autism and drug-resistant catatonia[J]. Brain Stimul, 2015, 8(6):1233-1235.
[28] 闻芳, 庞姣, 李小俚, 等. 经颅直流电刺激对孤独症谱系障碍儿童脑电的影响研究[J]. 中国生物医学工程学报, 2019, 38(5):566-572.
[29] Oberman LM, Rotenberg A, Pascualleone A, et al. Use of transcranial magnetic stimulation in autism spectrum disorders[J]. J Autism Dev Disord, 2015, 45(2):524-536.
[30] Muszkat D, Polanczyk GV, Dias TG, et al. Transcranial direct current stimulation in child and adolescent psychiatry[J]. J Child Adol Psychop, 2016, 26(7):590-597.