Abstract: Objective To investigate the helicobacter pylori (Hp) infection situation of pre-school children in Shenyang and to discuss the relative factors of Hp infection. Methods A total of 1 150 children in eight kindergartens were randomly selected with the method of cluster sampling.Serum IgG antibodies of Hp were measured.A structured questionnaire was sent to the parents of these children to obtain the related information. Results The Hp infection rate of pre-school children was 13.13% in Shenyang and it was trending up with increasing by ages.The Hp infection rate was higher significantly in children with digestive symptom than that in children without digestive symptom.Individual dinnerware and high income were the protective factors for the Hp infection of pre-school children, and age, low income, nibbling figures or toys, not often washing hands and family numbers with a history of stomach disease were the risk factors. Conclusions Pre-school children in Shenyang are susceptible to Hp infection, though their Hp infection rate is lower than that of the average rate in China.It is important for children to decrease the Hp infection by training them to have good health habits.

Key words: pre-school children, helicobacter pylori, epidemiology

摘要： 目的 了解沈阳市学龄前儿童Hp感染状况, 分析其相关影响因素。方法 采用整群抽样方法抽取8所幼儿园的1 150名儿童作为调查对象, 做血清学Hp-IgG抗体检测和家长问卷调查。结果 沈阳市学龄前儿童Hp感染率为13.13%, 随年龄增加而呈上升趋势。有胃肠道症状儿童Hp感染率(24.90%)明显高于无症状儿童(10.01%)。专用餐具和高经济收入是学龄前儿童Hp感染的保护性因素, 而年龄、低经济收入、啃手指/玩具、不常洗手和家族胃病史为危险因素。结论 本地区学龄前儿童Hp感染率低于全国平均水平, 但仍属易感人群。教育儿童从小养成良好卫生习惯对降低儿童Hp感染起重要作用。

关键词: 学龄前儿童, 幽门螺杆菌, 流行病学