journal1 ›› 2017, Vol. 25 ›› Issue (12): 1277-1280.DOI: 10.11852/zgetbjzz2017-25-12-25

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A case report on neonatal allergic colitis with similar symptoms to NEC and literature review

WEI Ming, LI Wen-bin, CHEN Pei-juan, CHANG Li-wen   

  1. Department of Pediatrics,Tongji Hospital Affiliated to Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei 430030,China
  • Received:2017-08-23 Online:2017-12-10 Published:2017-12-10
  • Contact: LI Wen-bin,


魏铭, 李文斌, 陈佩娟, 常立文   

  1. 华中科技大学同济医学院附属同济医院儿科,湖北 武汉 430030
  • 通讯作者: 李文斌,
  • 作者简介:魏铭(1990-),女,河北人,硕士在读,研究方向为新生儿疾病。

Abstract: Objective To analyze clinical manifestations of neonatal allergic colitis,in order to improve the diagnosis and treatment compared with neonatal necrotizing enterocolitis (NEC). Methods Clinical data of a case with neonatal allergic colitis mimicking NEC was retrospectively analyzed and relevant studies were reviewed. Results A 44-day-old infant developed abdominal distension,vomiting,bloody stool over and over again since totally artificial feeding at 4 days of age with abdominal radiological findings similar with NEC,and clinical symptoms relieved after fasting.Further foodborne allergens test showed cow's milk protein allergy.All symptoms disappeared after anti-infection and amino acid-based formula (AAF) feeding. Conclusions Neonatal allergic colitis may show similar symptoms with NEC,so clinical staff should pay attention to indentify different diagnosis.

Key words: neonate, allergic colitis, necrotizing enterocolitis

摘要: 目的 研究新生儿过敏性肠炎临床表现,并与新生儿坏死性小肠结肠炎(NEC)鉴别,提高其诊治水平。方法 回顾性分析1例类似NEC表现的新生儿过敏性肠炎患儿临床资料,复习相关文献。结果 患儿为44 d女婴,生后4 d开始完全人工喂养后出现腹胀、呕吐、血便等症状,腹部影像学呈NEC表现,禁食后临床征象缓解,并反复发生。进一步行食源性过敏原测定示牛奶蛋白过敏。经抗感染并换用氨基酸配方奶喂养后所有症状消失。结论 新生儿过敏性肠炎可呈NEC表现,临床上需注意鉴别。

关键词: 新生儿, 过敏性肠炎, 坏死性小肠结肠炎

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