journal1 ›› 2013, Vol. 21 ›› Issue (8): 789-792.

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Effects of serum sialic acid in pregnant women on neonatal physical growth

QIAO Yang1,2,BAI Zeng-hua2,WANG Jiong2,JIN Hua1,BAI Dan-dan1,MA Ya-ping1,GU Gui-xiong1   

  1. 1 Pediatric Research Institute of Soochow University,Suzhou,Zhejiang 215003,China;
    2 Shanxi Maternal and Child Health Hospital,Taiyuan,Shanxi 030013,China
  • Received:2013-06-18 Online:2013-08-06 Published:2013-08-06
  • Contact: GU Gui-xiong,E-mail:szggx000@163.com

孕妇血清唾液酸与正常新生儿的体格生长

乔阳1,2 ,白增华2,王熲2,金华1,柏丹丹1,马亚萍1,古桂雄1   

  1. 1 苏州大学儿科研究所,浙江 江苏 215003;
    2 山西省妇幼保健院,山西 太原 030013
  • 通讯作者: 古桂雄,E-mail:szggx000@163.com
  • 作者简介:乔阳(1970-) 女,山西人,副主任医师,博士学位,主要从事儿童生长发育研究。
  • 基金资助:
    江苏省普通高校研究生科研创新计划项目(CXLX11_0085);苏州市科技发展计划(SYS201145)

Abstract: Objective To investigate the correlation between the maternal serum sialic acid (SA) contents,umbilical cord serum SA contents,SA placenta transport rate with infant early growth and development. Methods Prospective cohort study was carried from early pregnancy,followed up to middle,late pregnancy and delivery.The relationships between maternal serum sialic acid at three stages of pregnancy,with offspring birth weight,height,head circumference and Kaup index were carried out. Results There were no significant differences in the neonatal birth weight,birth length,birth head circumference and Kaup index respectively in different serum SA contents in early pregnancy,middle pregnancy and late pregnancy(P>0.05).And there were no significant differences of umbilical cord serum SA and SA placenta transfer rate on neonatal outcome either(P>0.05). Conclusions There are no significant effects of maternal serum SA contents during pregnancy,fetal umbilical cord SA levels and SA placenta transfer rate on birth physical growth.SA doesn't cause obesity to infants.SA placenta transport rate can reflect the nutritional needs for fetal growth and development.

Key words: serum, sialic acid, physical growth, neonatal

摘要: 目的 研究孕妇不同妊娠期的血清唾液酸含量、脐血清唾液酸含量、唾液酸胎盘转运率与新生儿体格生长的关系。 方法 采取前瞻性队列研究的方法,从妊早、中、晚期至分娩时,分析孕期血清唾液酸水平与子代出生体重、身长、头围和Kaup指数的关系。结果 妊早、中、晚期孕妇不同血清唾液酸含量的新生儿出生体重、出生身长、出生头围及Kaup指数差异均无统计学意义(P>0.05);不同脐血清唾液酸和唾液酸胎盘转运率的新生儿出生体格差异亦无统计学意义(P>0.05)。 结论妊娠期的唾液酸含量、新生儿脐唾液酸含量和唾液酸胎盘运转率对新生儿出生体格生长无显著影响,唾液酸不会对婴儿造成肥胖的影响,唾液酸胎盘转运率只是反映唾液酸通过胎盘的一个度量,可以衡量胎儿当时生长发育的营养需求。

关键词: 血清, 唾液酸, 体格生长, 新生儿

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