doi:10.11852/zgetbjzz2016-24-11-16

Abstract

摘要： 新生儿B族溶血链球菌属β溶血链球菌(GBS)。由于对有危险因素的孕妇预防使用抗生素,新生儿GBS感染的发生率有所下降,但GBS耐药率有上升趋势。GBS耐药的主要血清型为血清型Ⅲ、Ⅰa、Ⅰb、Ⅱ、Ⅴ型,目前发现的大环内酯类抗生素耐药基因有ermA、ermB、mefA/E和linB等。疫苗的研究主要建立在血清型、ST-17基因的基础上,其中血清型主要集中于Ⅲ型及Ⅴ型。

关键词: 新生儿, 无乳链球菌, 耐药性, 耐药基因, 疫苗

CLC Number:

R179

苏锦珍,丁璐,吴本清. 新生儿B族溶血链球菌的耐药性及疫苗研究进展[J]. 中国儿童保健杂志, 2016, 24(11): 1174-1176.

0
/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://manu41.magtech.com.cn/Jwk_zgetbjzz/EN/10.11852/zgetbjzz2016-24-11-16

https://manu41.magtech.com.cn/Jwk_zgetbjzz/EN/Y2016/V24/I11/1174

[1] Wolny-Koladka K.Valuationof ITS-PCR and PCR MP techniques for Streptococcus agalactiae genetic differentiation[J].Med Dosw Mikrobiol,2014,66(3-4):149-160.
[2] Crespo-Ortiz Mdel P,Castaeda-Ramirez CR,Recalde-Bolaos M,et al.Emerging trends in invasive and noninvasive isolates of Streptococcus agalactiae in a Latin American hospital:a 17-year study[J].BMC Infect Dis,2014,3(8):1471-2334.
[3] Chang B,Wada A,Hosoya M,et al.Characteristics of group B streptococcus isolated from infants with invasive infections:A population-based study in Japan[J].Jpn J Infect Dis,2014,67(5):356-360.
[4] Florindo,Damiao V,Silvestre I,et al.Epidemiological surveillance of colonising goup B Steptococcus epidemiology in the Lisbon and Tagus Valley regions,Portugal(2015-2012):emergence of a new epidemic type IV/clonal complex 17 clone[J].Euro Surveill,2014,19(23):20825.
[5] Goudarzi G,Ghafarzadeh M,Shakib P,et al.Culture and real-time PCR based maternal screening and antibiotic susceptibility for group B Streptococcus:An Iranian experience[J].Glob J Health Sci,2015,7(6):45075.
[6] Soares GC,Alviano DS,da Silva Santos G,et al.Prevalence of group B streptococcus serotypes Ⅲ and Ⅴ in pregnant women of Rio de Janeiro,Brazil[J].Braz J Microbiol,2014,44(3):869-872.
[7] Stafford IA,Stewart RD,Sheffield JS,et al.Efficacy of maternal and neonatal chemoprophylaxis for early-onset group B streptococcal disease[J].Obstet Gynecol,2012,120(1):123-129.
[8] Clifford V,Heffernan HM,Grimwood K,et al.Variation in erythromycin and clindamycin resistance patterns between New Zealand and Australian B streptococcus isolates[J].Aust N Z J Obstet Gynaecol,2011,51(4):328-332.
[9] Garland SM,Cottrill E,Markowski L,et al.Antimicrobial resistance in group B streptococcus:the Australian experience[J].J Med Microbiol,2011,60(2):230-235.
[10] Ferrieri P,Lynfield R,Creti R,et al.Serotype IV and invasive group B streptococcus disease in neonates,Minnesota,USA,2000-2010[J].Emerg Infect Dis,2013,19(4):551-558.
[11] Bergseng H,Afset JE,Radtke A,et al.Molecular and phenotypic characterization of invasive group B streptococcus strains from infants in Norway 2006-2007[J].Clin Microbiol Infect,2009,15(12):1182-1185.
[12] Martins ER,Andreu A,Correia P,et al.Group B streptococci causing neonatal infections in Barcelona are a stable clonal population:18-year surveillance[J].J Clin Microbiol,2011,49(8):2911-2918.
[13] Wang P,Ma Z,Tong J,et al.Serotype distribution,antimicrobial resistance,and molecular characterization of invasive group B Streptococcus isolates recovered from Chinese neonates[J].Int J Infect Dis,2015,37(8):115-118.
[14] Verani JR,McGee L,Schrag SJ,et al.Prevention of Perinatal Group B Streptococcal Disease Revised Guidelines from CDC,2010[J].MMWR Recomm Rep,2010,59(RR-10):1-36.
[15] Paoletti LC,Guttormsen HK,Christian MS,et al.Neither antibody to a group B streptococcal conjugate vaccine nor the vaccine itself is teratogenic in rabbits[J].Human Vaccines,2008,4(6):435-443.
[16] Nuccitelli A,Rinaudo CD,Maione D,Group B Streptococcus vaccine:state of the art[J].Ther Adv Vaccines,2015,3(3):76-90.
[17] Yang HH,Mascuch SJ,Madoff LC,et al.Recombinant group B Streptococcus alpha-like protein 3 is an effective immunogen and carrier protein[J].Clin Vaccine Immunol,2008,15(7):1035-1041.
[18] Maeland JA,Afset JE,Lyng RV,et al.Survey of immunological features of the Alpha-like proteins of streptococcus agalactiae[J].Clin Vaccine Immunol,2015,22(2):153-159.
[19] Santi I,Grifantini R,Jiang SM,et al.CsrRS regulates group B streptococcus virulence gene expression in response to environmental pH:a new perspective on vaccine development[J].J Bacteriol,2009,191(17):5387-5397.
[20] Jiang S,Park SE,Yadav P,et al.Regulation and function of Pilus island 1 in group B Streptococcus[J].J Bacteriol,2012,194(10):2479-2490.
[21] Pannaraj PS,Edwards MS,Ewing KT,et al.Group B streptococcal conjugate vaccines elicit functional antibodies independent of strain O-acetylation[J].Vaccine,2009,27(33):4452-4456.
[22] Morozumi M,Wajima T,Kuwata Y,et al.Associations between capsular serotype,multilocus sequence type,and macrolide resistance in Streptococcus agalactiae isolates from Japanese infants with invasive infections[J].Epidemiol Infect,2014,142(4):812-819.

新生儿B族溶血链球菌的耐药性及疫苗研究进展

PDF

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

[1]	XIANG Wei. Early prevention of dyslipidemia in children and adolescents as well as cardiovascular health in adulthood [J]. Chinese Journal of Child Health Care, 2023, 31(7): 697-702.
[2]	WU Ting, LI Fei. Adverse factors in early life and the development and prevention of chronic diseases [J]. Chinese Journal of Child Health Care, 2023, 31(7): 703-706.
[3]	LIU Min, ZHANG Qian, YANG Ting, CHEN Jie, CHEN Li, DAI Ying, JIA Feiyong, WU Lijie, HAO Yan, LI Ling, ZHANG Jie, KE Xiaoyan, YI Mingji, HONG Qi, CHEN Jinjin, FANG Shuanfeng, WANG Yichao, WANG Qi, JIN Chunhua, LI Tingyu. Multi-center survey on serum folic acid in preschool children in China [J]. Chinese Journal of Child Health Care, 2023, 31(7): 713-717.
[4]	HUO Yanyan, LIU Zhongling, MA Ling, WU Dan, WANG Xiulian, QIU Xiaoyan, DOU Jiaying, REN Yuqian, LI Yicheng, HONG Xia, CHEN Jinjin. Status quo and risk factors for different body proportions of children under 2 years old in the real world [J]. Chinese Journal of Child Health Care, 2023, 31(7): 718-723.
[5]	YANG Yuru, WANG Hong, XU Shuhong, CAO Yanmei, MENG Xian, GE Dongmei. Association between bone development and vitamin K in children aged 0 to 14 years [J]. Chinese Journal of Child Health Care, 2023, 31(7): 746-750.
[6]	LI Mingzhu, WANG Jing, XIE Duoshuang. Research progress in the relationship between rapid catch-up growth and childhood obesity in small for gestational age infants [J]. Chinese Journal of Child Health Care, 2023, 31(7): 751-755.
[7]	CAO Hui, YAN Shuangqin, GUAN Hongyan. Influence of parent-child interaction on early childhood development outcome [J]. Chinese Journal of Child Health Care, 2023, 31(7): 770-774.
[8]	SUN Yan, GUO Fei , CHEN Zhiyan. Chain mediating role of family home reading and mother-child intimacy in intergenerational transmission of emotion regulation strategy [J]. Chinese Journal of Child Health Care, 2023, 31(6): 606-611.
[9]	ZHOU Yuanke, LI Yueyue, FANG Bo, SHENG Lulu, WU Wenyi, XI Xuan, LIU Qin. Behavior changes and influencing factors of firstborn children before and after the birth of the second children in a district of Chongqing [J]. Chinese Journal of Child Health Care, 2023, 31(6): 617-622.
[10]	TIAN Tian, SONG Jia, LI Jing, YUAN Hui, SHEN Mengmeng, DING Rong, ZHU Xiaohua, XU Hongze, HU Youfang. Family rearing environment and behavior problems of the second child aged 4 to 6 years in Jiangsu Province [J]. Chinese Journal of Child Health Care, 2023, 31(6): 623-628.
[11]	WANG Ziyang, HU Lei, LIU Jintong. Associations between family relationship and children's sleep [J]. Chinese Journal of Child Health Care, 2023, 31(6): 640-644.
[12]	WANG Dan, HUANG Chuican, FAN Lichun. Research progress in the effects of responsive feeding on sleep of infants and young children [J]. Chinese Journal of Child Health Care, 2023, 31(6): 656-660.
[13]	YU Yabin, WANG Jianhong, XU Qi, WANG Lei, ZHOU Bo, ZHANG Lili, WANG Xi, WANG Lin. Influencing factors of children with developmental stuttering [J]. Chinese Journal of Child Health Care, 2023, 31(6): 674-677.
[14]	LIANG Yijia, WU Honglin, HE Xiumei, HU Xiaohong, HE Xiyu. Types and frequencies of gene variants in idiopathic short stature children [J]. Chinese Journal of Child Health Care, 2023, 31(6): 678-683.
[15]	YING Jiali, CHEN Xiuqin, YANG Chen, HUANG Limei, YU Yan, GAO Xuemei. Moderating role of personality traits in the influence of violent video games on adolescent aggressive behavior [J]. Chinese Journal of Child Health Care, 2023, 31(6): 684-688.