Research progress in the effects of breast milk on T cell immune function in early life

doi:10.11852/zgetbjzz2022-1152

Abstract

Abstract: Different from adult, the immune systems of infants are not yet mature.Breast milk is a key condition for the maturation of immune function early in life, because that bioactive components in breast milk can not only directly promote the development of T cell immune function but also affect it indirectly by promoting the colonization of intestinal flora.As a result, the infection of pathogens and excessive inflammation damage to the body would be reduced.This review mainly summarizes the effects of breast milk on T cell immune function in early life, aiming to raise awareness of the importance of breast milk and to promote breastfeeding.

Key words: breast milk, T cell, immunity, intestinal flora, human milk oligosaccharides

摘要： 不同于成人的免疫系统,婴儿的免疫系统尚未发育成熟。母乳是生命早期免疫功能趋向成熟的关键条件,因为母乳中的生物活性成分能够直接影响并且可以通过促进肠道菌群的定植间接影响T细胞免疫功能,从而减少病原体的感染及过度炎症对机体的损害。本篇综述主要总结了母乳对生命早期T细胞免疫功能的影响,旨在加强人们对母乳重要性的认识,促进母乳喂养。

关键词: 母乳, T细胞, 免疫, 肠道菌群, 人乳低聚糖

CLC Number:

R392

ZHU Simin, ZHANG Wenting, TU Wenjuan. Research progress in the effects of breast milk on T cell immune function in early life[J]. Chinese Journal of Child Health Care, 2023, 31(8): 868-872.

朱思敏, 张雯婷, 屠文娟. 母乳对生命早期T细胞免疫功能影响的研究[J]. 中国儿童保健杂志, 2023, 31(8): 868-872.

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