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中国临床药理学与治疗学 ›› 2022, Vol. 27 ›› Issue (7): 834-840.doi: 10.12092/j.issn.1009-2501.2022.07.015

• 综述与讲座 • 上一篇    下一篇

新型麻醉镇痛药:艾司氯胺酮

贾涛1, 滕金亮2   

  1. 1河北北方学院研究生院,张家口 075000,河北;2河北北方学院附属第一医院麻醉科,张家口 075000,河北

  • 收稿日期:2022-04-11 修回日期:2022-07-05 出版日期:2022-07-26 发布日期:2022-08-11
  • 通讯作者: 滕金亮,男,主任医师,教授,硕士生导师,研究方向:麻醉药理。 E-mail: tengjinliang@126.com
  • 作者简介:贾涛,男,硕士,住院医师,研究方向:麻醉药理。 E-mail: 1134529749@qq.com

New narcotic analgesics: esketamine

JIA Tao1,2, TENG Jinliang2   

  1. 1 Graduate School of Hebei North University, Zhangjiakou 075000, Hebei, China; 2 Department of Anesthesiology, The First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, Hebei, China

  • Received:2022-04-11 Revised:2022-07-05 Online:2022-07-26 Published:2022-08-11

摘要: 出色的麻醉药艾司氯胺酮,效价较氯胺酮高,起效快,体内消除迅速,呼吸抑制轻,对循环系统影响小,在临床麻醉和镇痛领域中具有独特的优势。其亚麻醉剂量方案在各类手术和短小检查应用最广,相较于传统氯胺酮,所需起麻醉效力的剂量和精神副作用更低,镇痛效能更强,很有临床应用前景。

关键词: 艾司氯胺酮, 麻醉, 镇静, 疼痛治疗

Abstract: Esketamine is an excellent anesthetic with higher potency than ketamine, fast onset of action, rapid elimination from the body, mild respiratory depression, and little impact on the circulatory system. It has unique advantages in the field of clinical anesthesia and analgesia. Its sub-anesthetic dose regimen is the most widely used in various surgeries and short examinations. Compared with traditional ketamine, the dose required for anesthesia effect and mental side effects are lower, and the analgesic effect is stronger. It has great clinical application prospects.

Key words: esketamine, anesthesia, sedation, pain treatment

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