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中国临床药理学与治疗学 ›› 2003, Vol. 8 ›› Issue (6): 692-695.

• 研究原著 • 上一篇    下一篇

口服阿奇霉素、米诺环素、氟罗沙星治疗男性非淋菌性尿道炎的成本-效果分析

李东, 王晓玲, 孙业红   

  1. 暨南大学医学院第二附属医院、深圳市人民医院临床药学研究室,深圳 518020,广东
  • 收稿日期:2003-05-22 修回日期:2003-06-23 出版日期:2003-12-26 发布日期:2020-11-19
  • 通讯作者: 李东,男,在职研究生,副主任药师,主要从事医院药学和管理科学研究。Tel:0755-25533018-2817 E-mail:szlidong@163.com
  • 基金资助:
    深圳市卫生科技计划项目(No200006018)

Cost-effectiveness analysis of three schemes in treatment ofPatients with nongonococcal urethritis

LI Dong, WANG Xiao-LIng, SUN Ye-Hong   

  1. Department of ClinicalPharmacy,ShenzhenPeople Hospital&the Second Affiliated Hospital of the Medical College,Jinan University,Shenzhen 518020,Guangdong,China
  • Received:2003-05-22 Revised:2003-06-23 Online:2003-12-26 Published:2020-11-19

摘要: 目的 评价阿奇霉素与米诺环素、氟罗沙星口服治疗非淋菌性尿道炎的经济性,选择疗效佳、费用低的药物治疗方案。方法 选择采用3 种不同药物治疗方案(A 组:阿奇霉素po 0 .5 g qd×7 首剂加倍;B 组:米诺环素po 100 mg,bid×7;C 组:氟罗沙星po 0 .2 g,qd×7)的非淋菌性尿道炎病例共142例,运用药物经济学的成本-效果分析方法进行评价。结果 3 种方案的成本-效果比(C/E)分别为386 .43 元、427 .42 元、395 .71 元,总有效率分别为98 .21%、75 .56%、80 .49%(χ2=12 .07,P<0 .01)。结论 口服阿奇霉素成本-效果最佳;氟罗沙星市场价格偏高,建议厂商重新考虑中国市场的药品定价策略。

关键词: 药效学, 阿奇霉素, 米诺环素, 氟罗沙星, 药物经济学, 成本-效果分析, 定价, 非淋菌性尿道炎

Abstract: AIM: To evaluate the cost-effectiveness of azithromycin,minocycline and fleroxacin in treatment ofPatients with nongonococcal urethritis.METHODS: 142 cases including A,B and C schemes were evaluated by cost-effectivenessPrinciple.A scheme:received azithromycin 0.5 g,po,qd×7,and the first dose doubled;B scheme:received minocycline 100 mg,po,bid×7 ;and C scheme:received fleroxacin 0.2 g,po,qd×7.RESULTS: The cost of A,B and C schemes were RMB 386.43,427.42 and 395.71 yuan,respectively,and the effective ratio were 98.21%,75.56% and 80.49%(χ2=12.07,P<0.01),respectively.CONCLUSION: A scheme is the best one.

Key words: pharmacoeconomics, azithromycin, minocycline, fleroxacin, cost-effectiveness analysis, price, nongonococcal urethritis

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