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中国临床药理学与治疗学 ›› 2003, Vol. 8 ›› Issue (6): 699-700.

• 研究原著 • 上一篇    下一篇

金纳多治疗急性脑梗死的临床有效性和安全性评价

黄燕, 梁可珍, 张炳旺   

  1. 肇庆市第一人民医院神经内科,肇庆 526021,广东
  • 收稿日期:2003-07-10 修回日期:2003-07-22 出版日期:2003-12-26 发布日期:2020-11-19
  • 通讯作者: 黄燕,女,副主任医师,从事神经内科临床研究工作。Tel:0758-2860591

Clinical observation of effect of ginaton in treatment ofPatients with acute cerebral infarction

HUANG Yan, LIANG Ke-Zhen, ZHANG Bing-Wang   

  1. Department of Nerve,the FirstPeople' s Hospital of Zhaoqing,Zhaoqing 526021,Guangdong,China
  • Received:2003-07-10 Revised:2003-07-22 Online:2003-12-26 Published:2020-11-19

摘要: 目的 观察金纳多注射液治疗急性脑梗死的临床疗效。方法 选择发病在7 d 以内的急性脑梗死患者68 例,给予金纳多注射液20 ml 加入5%葡萄糖或生理盐水250 ml 中静脉点滴,共用3 周。结果 轻型40 例,显效率62 .5%,有效率95%,治疗前后神经功能缺损评分P<0 .01 。中型23 例,显效率39 .1%,有效率73 .9%,治疗前后神经功能缺损评分P<0 .05 。重型5 例,显效1 5,有效2 5,治疗前后神经功能缺损评分P>0 .05,总有效率85 .3%。结论 金纳多注射液是治疗急性脑梗死的有效药物,特别适用于轻、中型患者。

关键词: 药效学, 金纳多, 脑梗死, 疗效

Abstract: AIM: To observe the clinical effect of ginaton in treatment ofPatients with acute cerebral infarction.METHODS: 68 cases of acute cerebral infarction within 7 days of onset accepted three weeks ginaton therapy.20 ml of ginaton injection was added to 5% 250 ml glucose solution or 250ml normal saline solution for intravenous drip.RESULTS: Among 40 mild cases,the significant effective rate was 62.5%,and the score effective ratewas 95%.The neural function defective betweenPretreatment andPost-treatment showed a high significant difference(P<0.01).Among 23 middle cases,the significant effective rate was 39.1%,effective rate was 73.9%,and the neural function defective score betweenPre-treatment andPost-treatment showed significant difference(P<0.05).In 5 severe cases,1 case was significant effective,2 cases were effective,and the neural function defective score betweenPre-treatment andPosttreatment was no significant difference.The total effective rat was 85.3%.CONCLUSIONS: Ginaton injection is effective agent for treating acute cerebral infarction,especially mild cases.

Key words: pharmacodynamics, ginaton, cerebral infarction, curative effect

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