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中国临床药理学与治疗学 ›› 2006, Vol. 11 ›› Issue (9): 966-971.

• 综述 • 上一篇    下一篇

药物肠道吸收机制中转运载体、酶、电位的研究进展

郭源源, 王晖1, 陈垦2   

  1. 广东医学院药理教研室, 湛江 524023 , 广东;
    1广东药学院中药学院中药药理教研室, 2广东药学院临床医学院, 广州 510006 , 广东
  • 收稿日期:2006-04-19 修回日期:2006-05-28 出版日期:2006-09-26 发布日期:2020-11-05
  • 通讯作者: 王晖,男, 教授, 硕士生导师, 研究方向:皮肤粘膜药理学和数学药理学。E-mail:gdwanghui@tom.com
  • 作者简介:郭源源, 女, 在读硕士生, 研究方向:皮肤粘膜药理。Tel:13763028125 E-mail:vera-yuan@126.com

Mechanism profile of drug intestinal absorption about transporters , enzyme and potential

GUO Yuan-yuan, WANG Hui1, CHEN Ken1   

  1. Department of Parmacology , Guangdong Medical College , Zhanjiang 524023 , Guangdong , China;
    1Department of Parmacology for Chinese MeteriaMedica , Pharmacelltical College of Guangdong , 2Department of General Surgery , Pharmaceutical Gollege of Guangdong , Guangzhou 510006 , Guangdong , China
  • Received:2006-04-19 Revised:2006-05-28 Online:2006-09-26 Published:2020-11-05

摘要: 口服药物的肠道吸收是一个复杂的过程, 既取决于药物本身的理化特性, 又取决于机体的因素及吸收环境。本文从转运载体、酶、电位等几个方面综述了近年来药物肠道吸收机制的研究概况。

关键词: 肠道吸收, 转运载体, 酶, 电位, 机制

Abstract: The intestinal absorption of orally drug is a complicate process , which is not only dependent on physicochemical properties of drugs but also dependent on factors of organism and absorption conditions.This article summarized mechanism of drug intestinal absorption such as transporters , enzyme and potential.

Key words: intestinal absorption, transporters, enzyme, potential, mechanism

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