氯诺昔康在围手术期的应用进展

中国临床药理学与治疗学 ›› 2008, Vol. 13 ›› Issue (1): 16-20.

氯诺昔康在围手术期的应用进展

陈小非, 郭建荣

宁波大学医学院附属李惠利医院麻醉科, 宁波 315040, 浙江

收稿日期:2007-10-16 修回日期:2007-11-30 出版日期:2008-01-26 发布日期:2020-10-13
通讯作者: 郭建荣, 男, 博士, 教授, 硕士生导师, 研究方向:麻醉生理与药理学。Tel:0574-87018725 E-mail: guomzk@yahoo.com.cn
作者简介:陈小非, 男, 硕士, 主治医师, 研究方向:麻醉药理学。Tel:0574-87018726 　E-mail:chenxiaofei1980@163.com

Advancement of perioperative application of lornoxicam

CHEN Xiao-fei, GUO Jian-rong

Department of Anesthesiology, Affiliated Li Hui-li Hospital of Medical College of Ningbo University, Ningbo 315040, Zhejiang, China

Received:2007-10-16 Revised:2007-11-30 Online:2008-01-26 Published:2020-10-13

摘要/Abstract

摘要： 氯诺昔康是一种新型的非甾体类抗炎药,其不仅可抑制环氧化酶的活性, 还可抑制术后的免疫损伤, 其超前镇痛、术中及术后的镇痛疗效与阿片类药物相似, 可明显减少阿片类镇痛药物的用量。同时氯诺昔康具有半衰期短、不良反应少、耐受性良好等优点, 在围手术期可提供快速而稳定的镇痛效果。

关键词: 氯诺昔康, 围手术期, 镇痛, 非甾体抗炎药

Abstract: Lornoxicam is a new non-steroidal anti-inflammatory drug, it can inhibit the activity of cyclooxygenases and the immunologic injury after operation. Its efficacies on preoperative, operative period and postoperative analgesia are similar to those of opioid. Lornoxicam can decrease the dosage of opioid drugs and has the good qualities of short half-life, few adverse effects and satisfactory tolerance. Lornoxicam can provide rapid and stable analgesic effect in perioperative phase.

Key words: lornoxicam, perioperative phase, analgesia, non-steroidal anti-inflammatory drug

中图分类号:

R614

陈小非, 郭建荣. 氯诺昔康在围手术期的应用进展[J]. 中国临床药理学与治疗学, 2008, 13(1): 16-20.

CHEN Xiao-fei, GUO Jian-rong. Advancement of perioperative application of lornoxicam[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2008, 13(1): 16-20.

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