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中国临床药理学与治疗学 ›› 2009, Vol. 14 ›› Issue (11): 1292-1295.

• 临床药理学 • 上一篇    下一篇

本院急性胰腺炎抗菌药物应用回顾性分析

赵培西1, 郭颖华2, 刘渝1, 常瑛1, 王婧雯1, 朱艳荣1, 王志睿1, 文爱东1   

  1. 1第四军医大学西京医院药剂科,2第四军医大学西京医院临床免疫科, 西安 710033, 陕西
  • 修回日期:2009-09-30 发布日期:2020-10-26
  • 通讯作者: 文爱东,男, 主任药师, 硕士生导师, 主要从事药物代谢动力学及器官移植个体化用药研究。
  • 作者简介:赵培西, 硕士, 主管药师, 主要从事抗感染、消化临床药学研究。Tel:029-847754475-8021 E-mail:zhaopeixi1980@yahoo.com.cn

Retrospective analysis of antibacterial agents utilization in acute pancreatitis patients

ZHAO Pei-xi1, GUO Ying-hua2, LIU Yu1, CHANG Ying1, WANG Jing-wen1, ZHU Yan-rong1, WANG Zhi-rui1, WEN Ai-dong1   

  1. 1Department of Pharmacy, Xijing Hospital, Fourth Military Medical University, 2Department of Clinical Immunology, Xijing Hospital, Fourth Military Medical University, Xi'an 710033, Shaanxi, China
  • Revised:2009-09-30 Published:2020-10-26

摘要: 目的:调查本院急性胰腺炎抗菌药物应用现状, 探讨总结急性胰腺炎的抗菌药物合理应用原则及方法。方法:对2008 年1 月至12 月消化科93 例急性胰腺炎患者的临床资料和抗菌药物使用情况进行回顾分析。结果:93 例急性胰腺炎患者中, 轻型胰腺炎78 例, 占83.67 %;重症胰腺炎15 例, 占16.13 %。抗菌药物预防性应用存在过度用药现象, 抗菌药物联合应用方面大部分未做到按照指南用药, 用药疗程合理的仅占30 %。感染病例细菌培养送检率低, 经验用药现象严重。结论:急性胰腺炎抗菌药物应用存在不合理表现,应根据“个体化治疗结合指南”的原则及时合理选择抗菌药物。

关键词: 急性胰腺炎, 抗菌药物, 合理用药

Abstract: AIM: To examine the rational use of antibiotics in acute pancreatitis of Xi-Jing hospital. METHODS: Retrospective analysis 93 patients who were provided with antibiotics drugs of acute pancreatitis patients from January to December of 2008. RESULTS: There are 93 AP cases in the DegestionMedical Department.78 MAP cases account for 83.67 %, 15 SAP cases account for 16.13 %.Excessus-medication were found in prophylaxis utilization in antibacterials drug, for the bulk of antibacterials drug combination was unreasonable, the reasonable course of treatment only account for 30 %.The rates of bacterial culture were too low in infection cases, which caused severity experience medication. CONCLUSION: Generally, the choices of antibiotic are rational, but there are still substandard usage of antibiotics in hospital, and it's necessary to improve the management of rational usage of antibiotics.

Key words: acute pancreatitis, antibacterials, rational usage of antibiotics

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