薯蓣皂苷元药理活性及其机制研究进展

中国临床药理学与治疗学 ›› 2010, Vol. 15 ›› Issue (2): 233-237.

薯蓣皂苷元药理活性及其机制研究进展

岳蕾, 陈玲, 寇俊萍, 余伯阳

中国药科大学中药复方研究室,南京 210038,江苏

收稿日期:2010-01-14 修回日期:2010-01-30 出版日期:2010-02-26 发布日期:2020-09-18
通讯作者: 寇俊萍,女,博士,硕士研究生导师,研究方向:中药(复方)作用机理研究。Tel: 025-86185157 E-mail: junpingkou@163.com
作者简介:岳蕾,女,硕士,研究方向:中药有效成分作用机理研究。Tel: 025-86185157 E-mail: leieiyue@yahoo.com.cn
基金资助:
江苏省2009年度普通高校研究生科研创新计划项目(CX09S040Z)

Recent advances of diosgenin in its pharmacologic activities and mechanism

YUE Lei, CHEN Ling, KOU Jun-ping, YU Bo-yang

Department of Complex Prescription of TCM,China Pharmaceutical University,Nanjing 211198,Jiangsu, China

Received:2010-01-14 Revised:2010-01-30 Online:2010-02-26 Published:2020-09-18

摘要/Abstract

摘要： 薯蓣皂苷元(diosgenin,Dio)作为一种重要的甾体皂苷元,是生产甾体激素类药物的主要原料,其来源广泛,抗肿瘤、抗炎、心血管保护等活性显著,具有很高的药用价值,日益引起国内外学者的关注。本文重点综述了国际上近年来有关薯蓣皂苷元药理活性及其作用机制的研究进展,以供参考。

关键词: 薯蓣皂苷元, 药理活性, 抗肿瘤, 心血管保护, 抗炎

Abstract: Diosgenin, an important steroid sapogenin, is one of major precursors of synthetic steroids. It is rich in natural resources and has various significant activities such as anti-tumor, anti-inflammation, and cardiovascular-protection and so on. Recently, it causes increasing attention of scholars all over the world due to its valuable application in medicine. In this paper, thelatest international research advances of diosgenin in its pharmacologic activities and mechanism were reviewed.

Key words: Diosgenin, Pharmacological activity, Anti-tumor, Cardiovascular protection, Anti-inflammation

中图分类号:

岳蕾, 陈玲, 寇俊萍, 余伯阳. 薯蓣皂苷元药理活性及其机制研究进展[J]. 中国临床药理学与治疗学, 2010, 15(2): 233-237.

YUE Lei, CHEN Ling, KOU Jun-ping, YU Bo-yang. Recent advances of diosgenin in its pharmacologic activities and mechanism[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2010, 15(2): 233-237.

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