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中国临床药理学与治疗学 ›› 2019, Vol. 24 ›› Issue (1): 99-102.doi: 10.12092/j.issn.1009-2501.2019.01.017

• 医院药学之窗 • 上一篇    下一篇

伏立康唑注射剂临床应用情况及合理性分析

汪丽丽   

  1. 安庆市立医院药剂科,安庆 246003,安徽
  • 收稿日期:2018-07-03 修回日期:2018-08-03 出版日期:2019-01-26 发布日期:2019-01-25
  • 作者简介:汪丽丽,女,本科,主管药师、讲师,研究方向:抗菌药物合理使用。 Tel:0556-5223660 E-mail:wll98118@126.com
  • 基金资助:

    安徽省科技厅公益性研究联动项目(1604f0804033)

Clinical application and rationality analysis of voriconazole injection

WANG Lili   

  1. Department of Pharmacy, Anqing Municipal Hospital, Anqing 246003, Anhui, China
  • Received:2018-07-03 Revised:2018-08-03 Online:2019-01-26 Published:2019-01-25

摘要:

目的: 了解某医院伏立康唑注射剂的临床应用情况,分析药物使用的合理性。方法: 根据伏立康唑注射剂药品说明书,真菌感染治疗相关指南及参考文献制定合理性评价标准。利用医院HIS系统随机抽取某医院2016年1-12月份住院患者使用伏立康唑注射剂的病历,查阅病程记录及住院医嘱,进行合理性评价分析。结果: 本研究纳入的50份病历在伏立康唑注射剂给药途径、溶媒选用及溶媒用量方面均合理,但在用药指征、给药剂量、给药频次和给药疗程等方面存在不规范现象。结论: 该医院伏立康唑注射剂存在不合理使用现象,应进一步加强处方点评制度的实施,提高伏立康唑注射剂在临床的安全、合理使用。

关键词: 伏立康唑, 合理性, 评价分析

Abstract:

AIM: To investigate the clinical application of voriconazole injection in a hospital and to analyze the rationality of drug use. METHODS: Rationality evaluation criteria were formulated according to voliconazole injection drug instructions, fungal infection treatment guidelines and references. The hospital HIS system was used to randomly select the medical records of the hospitalized patients with voriconazole from Jan.2016 to Dec.2016, and the history of the hospital and the medical advice of the hospital were consulted, and the rationality of the hospital was analyzed. RESULTS: The 50 medical records included in this study are reasonable in the way of the administration of voriconazole injection, the selection of solvent and the amount of solvent, but there are some nonstandard phenomena in the indication of drug use, the dosage, the frequency of administration and the treatment course. CONCLUSION: The irrational use of voriconazole injection in this hospital should be corrected and the implementation of the prescription review system should be further strengthened to promote the safety and rational use of voriconazole injection in clinical practice.

Key words: voriconazole, rationality, evaluation

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