The value of serum calcitonin in bacterial meningitis

doi:10.12092/j.issn.1009-2501.2019.11.017

Abstract

Abstract:

Bacterial meningitis (BM) is a common central nervous system disease (CNS) in children, which poses a serious threat to the health of children.Therefore, it is of great importance to timely diagnose the type of encephalitis and promptly start treatment.At present, the gold standard for the diagnosis of BM is still cerebrospinal fluid examination, but the cooperation degree of children is low, the extraction of cerebrospinal fluid is difficult and the loss is large, and the cerebrospinal fluid culture takes a long time and the positive detection rate is low, so the significance of cerebrospinal fluid examination for the early treatment of BM is limited, and there is the possibility of delay of the disease.Serum procalcitonin (S-PCT) has high sensitivity and specificity to early prediction of bacterial infection.A large amount of evidence indicates that S-PCT is a useful tool for evaluating patients with known or suspected CNS infection, which can help diagnose BM and evaluate prognosis.This paper reviewes the current knowledge about S-PCT and its value in diagnosis and prognosis evaluation of BM.

Key words: serum procalcitonin, bacterial meningitis, diagnosis, prognosis

CLC Number:

R515

LI Wenshu, DONG Huaifu. The value of serum calcitonin in bacterial meningitis[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2019, 24(11): 1315-1320.

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