Abstract: Polysaccharide (PS) is one of the principal constituents in most traditional Chinese medicine. In recent years, the efficacy of PS has gradually become a popular aspect in fields of life science. Meanwhile, its pharmacokinetic research is still in its infancy. The classification, bioanalytical methods and pharmacokinetics of PS in recent years are summarized in this review. We hope to provide reference and guidance for researchers to study the pharmacokinetics of PS.

Key words: polysaccharides, bioanalytical method, pharmacokinetic