Welcome to Chinese Journal of Clinical Pharmacology and Therapeutics,Today is Chinese

Chinese Journal of Clinical Pharmacology and Therapeutics ›› 1998, Vol. 3 ›› Issue (2): 122-123.

Previous Articles     Next Articles

Protective Effect of Pulastiua chinensis on hepatic toxic injury induced by combining rifampin with isoniazidin mice

LU Xi-Ming, WANG Jian-Gang, WANG Xue-Ting, WU Ying-Ping, WANG Shu-Ying, LI Yan   

  1. Department of Pharmacology, Luoyang Medical College, Luoyang 471003
  • Received:1998-02-09 Revised:1998-03-30 Online:1998-06-26 Published:2020-12-01

PDF (PC)

150

Abstract: Aim Theprotective Effect of pulastiua chinensis (PC)on hepatic toxic injury induced by combinig rifampin with isoniazid was to be observedin mice.Methods Theliver index, level of SGPT, content of MDA of liver homogenate, and degree of liver cell injury were invest igatedin mice.Results PC could decreasethelevel of SGPT, theconte nt of MDA and thedeg ree of liver injury (P<0.01).Conclusions PChas theprotective Effect on hepatic toxic injury induced by combining rifampin with isoniazidin mice.

Key words: pulsatiua chinensis, rifampin, isoniazid, protective effect of liver

CLC Number: