Abstract: Aim To study the actions of Luofendeine and its component.Methods LD50 tests of Luofendeine and its component,heat-board text and body-twisting test of mice were pertormed to learn its analgesic and antiinflammatory actions.Results The analgesic action and antiinflammatory action were increased when codamine was mixed with buluofen by the rate of 13∶200,without increasing its toxicity.Conclution The complex prescription of Luofendeine is rational and can increase the analgesic action obviously.

Key words: luofendeine, analgesic, antiinflamation, aynergy