Abstract: Aim To evaluate the effect and safety of azithromycin injection producedin China and cefazolin in the treatment of respiratory tractinfections.Methods 50 patients with respiratory tractinfections weredivided randomly into two groups.Patients in the test grouprecieved azithromycin in the dosage of 250 mg·d^-1, qd for 5 div with double dosages at the fi rst timeand patients in the control grouprecieved cefazolin in the do sage of 2.0 g, bid, iv for 5 ~ 10 d.Results No statistical significant differences of overall clinical Effect wereobserved between two groups.The fully recovery, Effective and sidereaction rates for the test group were46.67 %, 90% and 3.3 %, respectively, and for control group the data were60 %, 95 %, and 0 %, respectively.Conclusion Azithromycin injection producedin China is effective and safe in the treatment of respiratory infections.

Key words: azithromycin, cefazolin, respiratory tractinfection