Abstract: AIM: To investigate effects of salvia mil-tiorrhiza injection on acute myocardial ischemia and hemorheology. METHODS: The acute myocardial is-chemia model and blood stasis model were established with high-dose adrenaline subcutaneous injection and be-ing socked in ice-water. The effect of salvia miltiorrhiza injection on the electrocardiogram J-point and T-ware of acute myocardial ischemia and the hemorheology of rat blood stasis model were observed. RESULTS: As com-pared with model groups, middle and high dose groups of salvia miltiorrhiza injection could obviously inhibit the rising of J-point and T-wave of the ischemic electrocardio-gram, all dose groups of salviamiltiorrhiza injection could prevent the ascending of blood viscosity and fibrinogen and hematocrit. CONCLUSION: salvia miltiorrhiza in-jection can effectively decrease blood viscosity and im-prove circulatation of coronary artery, and protect is-chemic myocardium.

Key words: acute myocardial ischemia, blood sta-sis, electrocardiogram, hemorheology, salvia miltiorrhiza injection