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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2003, Vol. 8 ›› Issue (3): 245-248.

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Advances in inhibiting the expression of Bax and cytoprotection1

CAO Zhi-Gang, YUAN Shou-Jun   

  1. Department of Pharmacology, Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850
  • Received:2003-02-19 Revised:2003-02-25 Online:2003-06-26 Published:2020-11-25

Abstract: Apoptosis is involved in a variety of physiological and pathological conditions.Bax is proapoptotic member in signal pathway of apoptosis.It will contribute influencing Bax, biological effects induced by Bax knock-out, and antisense nucleotides targeted to Bax-mRNA were reviewed in this article during recent years.

Key words: pharmacology, review, Bax gene, apoptosis, cytoprotection, antisense nucleotides

CLC Number: