Abstract: AIM: To evaluate efficacy and safety of the sinupret drops in the treatment of Chinese patients with acute sinusitis. METHODS: A randomized, positive-controlled (the capsules of gelomyrtol), parallelgroup, multi-central trial was carried out to evaluate the performance of the sinupret drops in Chinese patients. The assessment was blind to the investigators. RESULTS: There were no statistical differences in total curative efficacy and the approval of symptoms and signs between two groups (P >0.05).No adverse reactions were found during the trial. CONCLUSION: The sinupret drops is efficacy and safety in treatment of Chinese patients with acute sinusitis.

Key words: pharmacodynamics, sinupret drops, acute sinusitis, efficacy, safety, non-inferiority clinic trial