Experimental study on the inhibition of huangbaiye on HSV-2 in vitro

Abstract

Abstract: AIM: To study the effects of the huangbaiye in the treatment of recurrent genital herpes. METHODS: The inhibitory activity of huangbaiye on HSV-2 was observed from the cells cultured in vitro in comparison with cyclo-C and acyclovir. RESULTS: The huangbaiye showed notable direct inhibitory effects on HSV-2 in vitro.The minimal effective concentration was 2.5 g·L ^-1, the therapeutic index was 3, the inhibitory activity of huangbaiye (2.5 g·L^-1) was not less than that of cyclo-C, and the inhibition virus index was 2.83 in both huangbaiye and cyclo-C. CONCLUSION: Huangbaiye has inhibitory affect on HSV-2 in the treatment of recurrent genital herpes.

Key words: pharmacodynamics, huangbaiye, recurrent genital herpes, inhibitory, herpes virus Ⅱ

CLC Number:

YANG Zhi-Bo, OUYANG Heng, OU Bai-Sheng, TAN Jin-Hua. Experimental study on the inhibition of huangbaiye on HSV-2 in vitro[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2003, 8(3): 308-310.

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Experimental study on the inhibition of huangbaiye on HSV-2 in vitro

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