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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2003, Vol. 8 ›› Issue (4): 385-388.

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Anti-inflammatory and analgesic effects of wanlingwuxiangPAPPatcher

PANG Dan-Mei1, ZHENG Xiao-Liang, TANG Jian-Fei, lIU Xue-Li, QIAN Bo-Chu   

  1. Institute of Materia Medica,Zhejiang Academy of Medical Sciences,Hangzhou 310013,Zhejiang,China;
    1College ofPharmacy,Zhejiang University,Hangzhou 210006,Zhejiang,China
  • Received:2003-03-20 Revised:2003-03-25 Online:2003-08-26 Published:2020-11-19

Abstract: AIM: To observe anti-inflammatory and analgesic effects of wanlingwuxiangPAPPatcher in rats and mice.METHODS: The anti-inflammatory effect was studied by adjuvant arthritis in rats and croton oil method in mice.The analgesic effect was detected by writhing with acetic acid andlight-hot methods.The soft tissue injury test in rats and normal skin microcirculation test in mice werePerformed according toliterature.RESULTS: Significant effects of wanlingwuxiangPAPPatcher on rats adjuvant arthritis induced by Freund' s complete adjuvant,mice ear swelling caused by croton oil,and marked analgesic action in mice were observed.It could also relieve acute soft tissue injury and improve ear microcirculation.CONCLUSION: WanlingwuxiangPAPPatcher has effects of anti-inflammatory,analgesic,improvement of ear microcirculation,and remission of soft tissue injury actions.

Key words: pharmacology, wanlingwuxiangPAPPatcher, anti-inflammatory, analgesia, adjuvant arthritis

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