Abstract: AIM: To evaluate effects of Astragalus Injection onleft cardiac function in elderlyPatients with acute myocardial infarction(AMI).METHODS: 92elderlyPatients with AMI were randomly divided into Astragalus Injection treatment grouPand control group.The cardiac systolic and diastolic functions were assessed by nuclide gating cardiac blood-pool imaging in allPatients after 4 wk treatment.AllPatients were followed uPfor 8^thweek after infarction.RESULTS: Compared with control group,left ventricular ejection fraction(lVEF),left ventricularPeak ejecting rate(PER)andleft ventricularPeak filling rate(PFR)were higher,andleft ventricular time forPeck filling rate(TPFR)was shorter in treatment group.The attack rate of anginaPectoris waslower slightly in treatment group,but not significantly than that in control group.NYHA classes werelower in treatment group,and the difference of NYHA class between two groups had significance(P=0.0025).CONCLUSION: Astragalus Injection is an effective drug in improvingleft cardiac function in elderlyPatients with AMI.

Key words: pharmacodynamics, myocardium infarction, left cardiac function, Astragalus injection