Abstract: AIM: To evaluate the clinical therapeutic effects and safety oflow molecular weight heparin combined with xiangdan injection inPatients with acute cerebral infarction.METHODS: 100 cases ofPatients with acute cerebral infarction were divided into three groups.The combination grouP(40 cases)was treated withlow molecular weight heparin calcium of 5000 IU,sc,q 12 h,and xiangdan injection 40ml added into glucose injection 500 ml,iv gtt,qd,and thelow molecularweight heparin grouP(30 cases)was treated withlow molecular weight heparin calcium for injection only.The xiangdan grouP(30 cases)was treated with xiangdan injection only.The treating time was 10d in three groups.RESULTS: The cure rate in the combination grouPwas the highest among the three groups(P<0.05),and the rate of adverse reaction did not show significance(P>0.05)among three groups.CONCLUSION: Thelow molecular weight heparin combined with xiangdan injection is effective and safe in the treatment ofPatients with acute cerebral infarction.

Key words: pharmacodynamics, low molecular weight heparin, xiangdan, acute cerebral infarction, drug evaluation