Abstract: Recruitment of eligible subjects is of para-mount importance and probably the most difficult and changeling aspect of a clinical trial. Ethic review of sub-jectsJ recruitment mainly includes the mode of recmit-ment,the selection of subject population, recompense and incentives to subjects. For reviewing of mode of re-cruitment,respect for privacy and voluntary participation, avoiding any possibility of coercion or undue influence must be taken into account; while for reviewing of selec-tion of subject population, apportion of research burdens and benefits must be equally considered among population and the representative of study cohort? The reasonable recompense and free from undue inducement must be con-sidered when reviewing recompense and incentives to sub-jects.

Key words: clinical trial, institutional review board, ethic review, subjects recruitment