Abstract: AIM: To observe the effects of misoprostol used for intenerating cervical and ease pain in hysteroscopy.METHODS: 63 of 107 cases were randomly chosen as the group of misoprostol, and 200 μg misoprostol was taken orally 1h before hysteroscopy.Another 44 cases were taken as the group of antitheses, and no medication was taken before hysteroscopy.RESULTS: The diameter of cervical, hemorrhage, the rate of PAAS and bellyache in the group of misoprostol were lower than that in the group of antitheses.CONCLUSION: 200 μg misoprotol orally 1h before hysteroscopy is an advantageous and ideal method with alleviating pain from wound, reducing manipulation, decreasing hemorrhage, reducing PAAS happening in intenerating cervical.

Key words: misoprostol, hysteroscope, intenerating cervical, ease pain, PAAS