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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2005, Vol. 10 ›› Issue (12): 1368-1371.

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Effects of alltride on gastric ulcerand promoting bowl movement

LIAO Hui-fang, LIAO Xue-zhen, ZHOU Jiao-yao   

  1. Department of Pharmacology,GuangzhouUniversity of TCM,Guangzhou 510405,Guangdong,China
  • Received:2005-09-02 Revised:2005-10-21 Online:2005-12-26 Published:2020-11-11

Abstract: AIM: To study the effects of alltride on experimental gastric ulcerand promoting bowl movement.METHODS: Applying experimental gastric ulcermodels induced by alcohol and hydrochloric acid,ligating pylorus,indomethacin,acetic acid,calculated the index of gastric ulcer.Applying dry stool constipations in mice the first defecation time,moist dejection amounts were observed.In small intestinal propelling test in normal mice,small intestinal contents (charcoal Powder) ropelling ratio was observed.RESULTS: Alltride reduced the index of ulcers in above experimental gastric ulcermodel rats(P<0.05 orP<0.01).KZS shortened the first defecation time and increase moist dejection amounts in dry stool constipations mice and improve apparently intestinal peristalsis (P<0.05 orP<0.01).CONCLUSION: Alltride has antiulcereffects in rats and the action of moistening the intestines and promoting bowl movement.

Key words: alltride, gastric ulcermodel antiulcer, constipation

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