Design of dose titration in clinical trial of new drug

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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2005, Vol. 10 ›› Issue (4): 479-480.

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Design of dose titration in clinical trial of new drug

ZHENG Qing-Shan, SUN Rui-Yuan

Anhui Provincial Center for Drug Clinical Evaluation &Yijishan Hospital of Wannan Medical College, Wuhu 241001,China

Received:2005-04-01 Revised:2005-04-18 Online:2005-04-26 Published:2020-11-19

Abstract

Abstract: Titration to optimal effect is the central principle in the treatment of diseases with medications, and an important approach for the study of dose-response relationship.This paper lists different types, characteris-tics and important pointsin the design.An example of ro-suvastain calcium is given by the design in clinical trail.

Key words: clinical trial, dose-response relation-ship, changeable dose design, blood lipid, trail design, rosuvastatin

CLC Number:

R

ZHENG Qing-Shan, SUN Rui-Yuan. Design of dose titration in clinical trial of new drug[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2005, 10(4): 479-480.

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Design of dose titration in clinical trial of new drug

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