Abstract: AIM:To evaluate the efficacy and safety of the amoxicillin and potassium clavulanate chewable tablets .METHODS:With the amoxicillin and clavu- lanate potassium tablets serving as the reference, a total of 120 patients with respiratory apparatus or urinary system infection were treated with amoxicillin and potassium cla- vulanate chewable tablets in the randomized double-blind- ed multicentre research .RESULTS:There was no sig- nificant difference( P >0 .05) between the tested tablets and the reference on their clinical efficacy, antibiosis effi- cacy and safety .The tested tablets were effective to respi- ratory apparatus or urinary system infection,with effective rate at 88 .33 % and recovery rate at 76 .67 %.CON- CLUSIONS:The amoxicillin and potassium clavulanate chewable tablet is an effective and safe antibiotic agent in the treatment of patients with respiratory apparatus or uri- nary system infection .

Key words: amoxicillin and potassium clavulanate chewable tablets , clinical trial , efficacy , safety