Abstract: AIM: To investigate the clinical effects of complex capsules of Qinghuang in the treatment of patients with chronic myelocytic leukemia (CML). METHODS: The complex capsules of Qinghuang are composed of indigo naturalis, realgar, etc.The volunteers with chronic myelocytic leukemia received the clinical therapy of complex capsules of Qinghuang.The analysis of hemogram and evaluation of survival and prognosis in patients treated with and without complex capsules of Qinghuang were observed. RESULTS: We got the entire information and data of follow-up visit of patients after they were treated with complex capsules of Qinghuang for a long time.Among 6 patients, 4 of them were complete remission (CR) and 2 were partial remission (PR), and 1 patient had survived for 16 years.All patients did not deteriorate into acute transformation phase. CONCLUSION: The complex capsules of Qinghuang have a good therapeutic efficacy on the treatment of patients with chronic myelocytic leukemia, and they have only some gentle side effects.The present study provides some clinical evidences for the treatment of CML with traditional Chinese medicine and arsenical in the future.

Key words: complex capsules of Qinghuang, chronic myelocytic leukemia, indigo naturalis, realgar