Abstract: AIM: To observe curative effect of longterm use of statins on blood lipid and left ventricular function in patients with myocardial infarction accompanied by hyperglycemia. METHODS: 59 patients with myocardial infarction were randomly divided into two groups. These patients were treated with statins (euglycemia patients, n=25 ;hyperglycaemia patients, n=34). The levels of blood lipid, LVEDD, LVESD, LVEDV, LVESV and LVEF were measured 0 and 2 years after the onset of observation. RESULTS: The long-term use of statins decreased levels of TC and LDL-C in patients with euglycemia or hyperglycemia (P<0.01 or P<0.05) , and there was a significant difference between the two groups. LVEF in two groups was statistically different (P<0.05) before and after the drugs were used. CONCLUSION: The long-term use of statins has more curative effect for patients with euglycemia than those with hyperglycemia. Left ventricular function becomes better in patients with myocardial infarction accompanied by euglycemia or hyperglycemia.

Key words: statins, myocardial infarction, heart Failure