Discussion and considerations on the mutant prevention concentration and mutant selective window

Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2008, Vol. 13 ›› Issue (1): 21-24.

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Discussion and considerations on the mutant prevention concentration and mutant selective window

HUANG Han^1,2, LIU Shi-kun²

¹Hunan Medical College, Changsha 410000, Hunan, China;
²Department of Pharmacy, Third Affiliated Hospital of Xiangya Medical College, Central South University, Changsha 410013, Hunan, China

Received:2007-09-25 Revised:2007-10-21 Online:2008-01-26 Published:2020-10-13

Abstract

Abstract: The mutant prevention concentration (MPC) and mutant selective window (MSW) were new conceptive theories of resistance mutantion preventation which were raised by Zhao X and Drlica K et al. In this paper, the conceptions of MPC and MSW and some could related issues were discussed. Finally how to prevent resistance mutantion was reviewed.

Key words: mutant prevention concentration, mutant selective window, minimum inhibitory concentration, resistance mutantion

CLC Number:

R969

HUANG Han, LIU Shi-kun. Discussion and considerations on the mutant prevention concentration and mutant selective window[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2008, 13(1): 21-24.

References

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Discussion and considerations on the mutant prevention concentration and mutant selective window

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