GNB3 C825T and essential hypertension

Abstract

Abstract: G protein plays an important role in the process of signal transduction.It mediates many intracellular effects of blood vessel competent and proliferation.So pharmacologists are very interested in the relation of its polymorphisms and cardiovascular diseases particular essential hypertension.GNB3 C825T polymorphism distributes differently in various populations. We focus on the relation of GNB3 C825T polymorphism with essential hypertension in different populations, and therapeutic effects on hypotensive drugs.

Key words: Gprotein, GNB3 C825T, polymorphism, essential hypertension, therapeutic effects

CLC Number:

R968
R544.1

HUANG Hai-ying, ZHOU Hong-hao. GNB3 C825T and essential hypertension[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2008, 13(3): 355-360.

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