Abstract: AIM:To compare the effect and safety of different epidural anesthesia methods on cesarean section in plateau area.METHODS:Sixty ASA I-IIpatients undergone cesarean section were randomly allocated into three groups :lidocaine hydrochloride group (group Ⅰ, epidural anesthesia with 2% lidocaine hydrochloride), lidocaine carbonation group(group Ⅱ, epidural anesthesia with 1.73% lidocaine carbonation), and bupivacaine group(group Ⅲ, spinal anesthesia with 0.5% hyperbaric bupivacaine).The anaesthesia onset time, consummate time, highest plane, and fetal disengagement time of three groups were compared.The blood pressure, heart rate, adverse reaction of patients in each group were recorded.RESULTS: Compared with group Ⅰ, group Ⅱhad faster anaesthesia onset time, shorter consummate time and fetal disengagement time.Compared with group III, group Ⅱ had less adverse reaction and less effect on blood pressure and heart rate of patients, there were significant difference.CONCLUSION:Epidural anesthesia with lidocaine carbonation on cesarean section in plateau hypoxia circumstances has the characteristics of faster anaesthesia onset time, shorter anaesthesia consummate time and exact effect, and moreover, it has less effect of haemodynamics and adverse reaction and it can elevate safety in parturient and neonate operation.Therefore, it is a safe and reliable anaesthesia method for cesarean section in plateau area.

Key words: lidocaine carbonation, cesarean section, plateau area