Abstract: AIM: To evaluate the clinical therapeutic effect of Heshouwu granula on type 2 diabetic hyperlipemia.METHODS: 106 cases with type 2 diabetic hyperlipemia were divided into two groups :52 in test group and 54 in control group.In addition of their conventional treatment of hypoglycemic agents and diabetic diet and exercise, Heshouwu granulas were used in test group, the dosage was 3 g (one pouch) once per day.Simvastatin of 10 mg once per day was used in control group.Both groups were treated for consecutive 45 days.RESULTS: The symptoms in test group were improved, the scores of the symptoms were lowered significantly compared with both that before treatment (P<0.05) and that of compare group (P<0.01) ;in test group, the blood glucose was significantly lowered compared with that before treatment and that in control group(P<0.05, P<0.01).The 2-hour postprandial glucose in control group was decreased significantly compared with that in control group(P<0.05).The urine glucose was decreased significantly than that before treatment (P<0.05).The cholesterol and triglyceride in test group were decreased significantly compared with those before treatment (P<0.05) but not significantly compared with those in control group(P>0.05).There were 12 cases with market effect and 29 with effectiveness in test group, the total effective rate was 78.85 %, which was significantly effective than that in control group(P<0.05).CONCLUSION: Heshouwu granula is effective for treating type 2 diabetic hyperlipemia, and the efficiacy is better than simvastatin.

Key words: Heshouwu granula, type 2 diabetic hyperlipemia, clinical therapeutic effect